Puberty and disease activity in JIA
نویسندگان
چکیده
Methods All consecutive JIA patients aged 10-24 years were asked to participate in this observational follow-up study. Demographic and disease related items were obtained yearly as well as Tanner puberty stages: Pubic Hair Girls (PHG), Breast stage (Bre), Menarche (Men), Pubic Hair Boys (PHB), Genital Stage (Gen). Reference Values were obtained from the Dutch National Growth Study. Median age at reaching each pubertal stage was estimated by Kaplan Meier survival estimates based on the data from patients of Caucasian origin and younger than 21 years. Non parametric tests are used to determine significant differences.
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